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NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS
专利权人:
GALAPAGOS NV
发明人:
MAMMOLITI, Oscar,JANSEN, Koen,MENET, Christel,PALISSE, Adeline,TRICARICO, Giovanni,EL BKASSINY, Sandy,JAUNET, Alexis,ALLART, Brigitte,DUTHION, Béranger,BREBION, Franck Laurent
申请号:
SG11202000032P
公开号:
SG11202000032PA
申请日:
2018.06.21
申请国别(地区):
SG
年份:
2020
代理人:
摘要:
The present invention discloses compounds according to Formula (I) Wherein R1, R2, L, A1, A2, A3, Cy and the subscript n are as defined herein. The present invention relates to antagonists compounds of sphingosine 1-phosphate (SIP) receptor, methods for their production, pharmaceutical compositions comprising the same, and methods of treatment using the same, for the prophylaxis and/or treatment of diseases involving fibrotic diseases, inflammatory diseases, respiratory diseases, autoimmune diseases, metabolic diseases, cardiovascular diseases, and/or proliferative diseases by administering the compound of the invention.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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