Timothy J. Maines,Bernardus Machielse,Bharat M. Mehta,Gerald Wisler,Michael Davidson,Peter Ralph Wood
申请号：
US14370730
公开号：
US20150004224A1
申请日:
2013.01.04
申请国别(地区):
US
年份:
2015
代理人:
摘要：
DPA-enriched pharmaceutical compositions of polyunsaturated fatty acids in free acid form, therapeutic methods for their use, and processes for refining the compositions from fish oil are presented. Also provided are methods of treating hypertriglyceridemia (200 mg/dL-500 mg/dL) by adjunctive administration of a statin and the pharmaceutical compositions described herein. Further treatment methods include, inter alia, treatments to increase plasma EPA:AA ratios, treatments to decrease ApoCIII levels, and treatments to reduce or prevent resistance to platelet aggregation inhibitors.
