Takashi Tsukamoto,Barbara Stauch Slusher,Dana V. Ferraris,Camilo Rojas,Niyada Hin,Bridget Duvall
申请号：
US14420236
公开号：
US20150218156A1
申请日:
2013.08.08
申请国别(地区):
US
年份:
2015
代理人:
摘要：
D-amino acid oxidase (DAAO) inhibitors and methods of their use, either alone or in combination with D-serine or D-alanine, to facilitate allosteric activation of NMDA receptor-mediated neurotransmission and methods of their use as therapeutic agents for treating a subject afflicted with one or more cognitive-disorders, such as schizophrenia, including subjects suffering from negative symptoms and cognitive impairments, post-traumatic stress disorder (PTSD), or pain, are disclosed.
