FIBRONECTIN BASED SCAFFOLD DOMAIN PROTEINS THAT BIND IL-23

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专利权人:

Bristol-Myers Squibb Company

发明人:

Ruchira DASGUPTA,Alex Bush,Lumelle Schneeweis,Linda Engle

申请号：

US14553379

公开号：

US20150274806A1

申请日:

2014.11.25

申请国别(地区):

US

年份:

2015

代理人:

摘要：

The present invention relates to fibronectin based scaffold domain protein that bind interleukin 23 (IL-23), specifically the p19 subunit of IL-23. The invention also relates to the use of the innovative proteins in therapeutic applications to treat autoimmune diseases. The invention further relates to cells comprising such proteins, polynucleotide encoding such proteins or fragments thereof, and to vectors comprising the polynucleotides encoding the innovative proteins.

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