HANSEN, HANS J.,GRIFFITHS, GARY L.,LEUNG, SHUI-ON,MCBRIDE, WILLIAM J.,QU, ZHENGXING
申请号：
CA2690395
公开号：
CA2690395C
申请日:
1999.06.22
申请国别(地区):
CA
年份:
2013
代理人:
摘要：
The present invention relates to a bi-specific antibody or antibody fragment having at least one arm that specifically binds a targeted tissue and at least one other arm that specifically binds a targetable conjugate. The targetable conjugate comprises a carrier portion which comprises or bears at least one epitope recognizable by at least one arm of said bi-specific antibody or antibody fragment. The targetable conjugate further comprises one or more therapeutic or diagnostic agents or enzymes. The invention provides constructs and methods for producing the bi-specific antibodies or antibody fragments, as well as methods for using them.
