John McWhirter,Cagan Gurer,Lynn Macdonald,Andrew J. Murphy
申请号:
US16001070
公开号:
US20180271070A1
申请日:
2018.06.06
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Non-human animals, cells, methods and compositions for making and using the same are provided, wherein the non-human animals and cells comprise a humanized a proliferation-inducing ligand gene. Non-human animals and cells that express a human or humanized a proliferation-inducing ligand protein from an endogenous a proliferation-inducing ligand locus are described.