GRAY, JEFFREY, LYLE,AMARASINGHE, KANDE,CLARK, CYNTHIA, MONESA,MAIER, MATHEW, BRIAN,NICHOLS, RYAN
申请号：
NZ57440707
公开号：
NZ574407A
申请日:
2007.06.27
申请国别(地区):
NZ
年份:
2012
代理人:
摘要：
Disclosed herein sulfamic acid derivatives of the given formula, wherein R is either substituted or unsubstituted thiazol-2-yl or thiazol-4-yl with the substituents are as defined within the specification, processes for their preparation, compositions comprising said compounds. Said compounds are useful as human protein tyrosine phosphatase beta (HPTP-B) inhibitors and as such are useful in regulating angiogenesis, treating skeletal muscle and myocardial ischemia, stroke, coronary artery disease, peripheral vascular disease, coronary artery disease, promoting the growth of skin graft replacements and for vascularizing ischemic tissue.
