The present invention relates to a composition of balloon flower roots fermented with mushroom mycelium having an excellent anti-inflammatory and anti-oxidant activity, which is characterized by that balloon flower roots are inoculated with mushroom mycelium and fermented. The composition of balloon flower roots fermented with mushroom mycelium obtained according to the present invention shows an excellent anti-inflammatory and anti-oxidant effect, thereby being able to be used for a food composition or a pharmaceutical composition including the composition of balloon flower roots fermented with mushroom mycelium as an active ingredient for prevention and/or treatment of inflammatory diseases.COPYRIGHT KIPO 2015본 발명은 우수한 항염 및 항산화 활성을 갖는 도라지 버섯균사체 발효 조성물에 관한 것으로서, 도라지에 버섯균사체를 접종시켜 발효시킨 것을 특징으로 하며, 본 발명에 따라 수득되는 도라지의 버섯균사체 발효 조성물은 우수한 항염 및 항산화 효과를 나타냄으로써 도라지 버섯균사체 발효 조성물을 유효성분으로 함유하는 항염증 예방 치료를 위한 식품조성물 또는 약학조성물로 이용될 수 있다.