MCWHIRTER, John,GURER, Cagan,MACDONALD, Lynn,MURPHY, Andrew J.
申请号:
EP20180185303
公开号:
EP3409110(A1)
申请日:
2014.11.10
申请国别(地区):
欧洲专利局
年份:
2018
代理人:
摘要:
Non-human animals, cells, methods and compositions for making and using the same are provided, wherein the non-human animals and cells comprise a humanized B-cell activating factor gene. Non-human animals and cells that express a human or humanized B-cell activating factor protein from an endogenous B-cell activating factor locus are described.