Novel anticancer agents including, but not limited to, antibodies and immunoconjugates bound to human folate receptor 1 are provided. Further provided are methods of using the agent, antibody or immunoconjugate, such as a method of inhibiting tumor growth.提供新穎的抗癌劑,其包括但不限於結合至人類葉酸受體1的抗體與免疫綴合物。進一步提供使用該藥劑、抗體或免疫綴合物的方法,例如抑制腫瘤生長的方法。