Nanoparticles containing azolium and N-heterocyclic carbene compounds and use thereof

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专利权人:

National Dong Hwa University

发明人:

Ivan Jyh Biau Lin,Tina H. T. Hsu,Shiu-Huey Chou

申请号：

US15343883

公开号：

US09855280B2

申请日:

2016.11.04

申请国别(地区):

US

年份:

2018

代理人:

摘要：

The present application provides a composition comprising a core formed by gold nanoparticle, a compound of Formula (I):wherein dashed lines in Formula (I) represent (i) with or without an attachment of benzol group, (ii) a delocalized bond where shown within a ring； R1 is hydrogen or a halogen； R2 is a linker selected from C6-20 alkyl or polyethylene glycol； R3 is C1-20 alkyl, C1-20 substituted alkyl, hexadecanyl amido, pyridinyl, benzyl or pyrimidinyl； and a compound of Formula (II):wherein dashed lines, R1, R2 and R3 are defined as in Formula (II), and M is a metal. The composition has an inhibition ability against a cancer.

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