Ana Maria Jiménez Redondo,Angel Munoz Ruiz,Nuria Sanz Menéndez,Femando Martinez-Alzamora Garcia,Antonia Gomez Calvo,Gonzalo Hernandez Herrero
申请号：
GB201215436
公开号：
GB2490840B
申请日:
2010.03.01
申请国别(地区):
GB
年份:
2017
代理人:
摘要：
The present invention relates to a novel liquid pharmaceutical composition that contains ibuprofen in the form of a salt formed with a basic amino acid and codeine or a pharmaceutically acceptable codeine salt, for oral administration, and in particular the composition contains an ibuprofen salt or a basic amino acid such as arginine, lysine or mixtures thereof. Furthermore, the invention relates to a method for preparing said pharmaceutical composition and also the use thereof, preferably in paediatrics, for the manufacture of a drug that can be used to treat moderate-to-severe pain, inflammation, fever and/or other illnesses in which ibuprofen and/or codeine are traditionally used principally as analgesic. The composition of the invention exhibits good stability after three years under different temperature and relative humidity conditions.
