The problem of the present invention is to provide a composition for enhancing transdermal absorption of a drug, which shows a sufficiently high enhancing effect on transdermal absorption of an acidic drug.A composition for enhancing transdermal absorption of an acidic drug, comprising a polyvalent alcohol having 3 - 8 carbon atoms, a higher alcohol having 12 - 20 carbon atoms and an organic amine having 2 - 9 carbon atoms.