Jo Van Ginderachter,Patrick De Baetselier,Nick Devoogdt,Tony Lahoutte,Damya Laoui,Kiavash Movahedi,Geert Raes,Steve Schoonooghe
申请号：
US14402301
公开号：
US09556273B2
申请日:
2013.03.15
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The disclosure relates to immunoglobulin single variable domains directed against human macrophage mannose receptor (MMR) and their uses in the field of oncology. More specifically, it concerns immunoglobulin single variable domains, including single-domain antibodies (sdAbs), against human MMR and their use in targeting and in vivo imaging of tumor-associated macrophages, with applications in the field of cancer diagnostics and therapeutics and monitoring of the disease.
