The Regents of the University of Colorado; a body corporate
发明人:
Priya N. Werahera,John Daily,M. Scott Lucia,Adrie van Bokhoven,E. David Crawford,Frank Barnes
申请号：
US16036323
公开号：
US20180360320A1
申请日:
2018.07.16
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Methods and systems for in vivo classification of tissue are disclosed. The tissue is irradiated with light from multiple light sources and light scattered and fluoresced from the tissue is received. Distinct emissions of the sample are identified from the received light. An excitation-emission matrix is generated (1002). On-diagonal and off-diagonal components of the excitation-emission matrix are identified (1004, 1006, 1008). Spectroscopic measures are derived from the excitation-emission matrix (1014), and are compared to a database of known spectra (1016) permitting the tissue to be classified as benign or malignant (1018). An optical biopsy needle or an optical probe may be used to contemporaneously classify and sample tissue for pathological confirmation of diagnosis.
