CURRIE, MARK G.,HASHASH, AHMAD,LAVINS, BERNARD JOSEPH,HALL, MICHAEL,KARASIK, SILVA
申请号：
CA3070082
公开号：
CA3070082A1
申请日:
2018.07.19
申请国别(地区):
CA
年份:
2019
代理人:
摘要：
Methods and formulations of reducing one or more symptoms of gastroesophageal reflux disease (GERD) in a human patient with symptomatic GERD not completely responsive to proton pump inhibitors (PPIs). The patient is administered a therapeutically effective amount of an enteric coated gastro-retentive oral dosage form in the form of a tablet of a bile acid sequestrant dispersed in a polymeric matrix consisting essentially of poly(alkylene)oxide and one or more filler or compressing agent such that the patient experiences a clinically meaningful reduction in one or more symptoms of GERD.
