A respiratory cuff pressure regulator system is provided for use with a breathing tube equipped with an inflatable cuff, a tubule extending from the cuff and having a distal end communicating with an inside of the cuff, a proximal end having an inlet for inflating the cuff. The system includes a sealed housing enclosing an inflatable member and in fluid communication with the tubule, the sealed housing having an air inlet bore in fluid communication with the tubule inlet and with the interior of the inflatable member. A valve in the inlet bore is normally closed and opens for inflation of the inflatable member and ultimately the respiratory cuff. An equalizing biasing member in the sealed housing exerts a bias against the inflatable member. A pressure relief valve is provided in fluid communication with the tubule and is preset to open upon pressure in the tubule exceeding a predetermined amount.
