Isoindolinona compounds. The compounds are isoindolinona modulating GPR119 and are useful for the Prevention and / or treatment of diabetes, obesity, dyslipidemia and Related Disorders.Also refers to the use of compounds of isoindolinona as active principles in medicinal and Pharmaceutical compositions containing same.Claim 1: a compound of the formula (1), in which X is n or C - r u00b9 u1d43； is cr u00b3 u00b9r u00b3 u00b3, nr u00b3 u00b9,Cr u00b3 u00b9r u00b3 u00b3 - nr u00b3 u00b9 or cr u00b3 u00b9 = N； r u00b3 u2070 is H OR (cr u00b9 u00b9r u00b9 u00b2) u2099 - r u00b3 u00b2； r u00b3 u00b9 is H OR (cr u00b9 u00b9r u00b9 u00b2) u2099 - r u00b3 u00b2； r u00b3 u00b3 is H or alkyl c u2081 u208b u2086； r u00b9 u00b9, r u00b9 u00b2 are, independently of one another, c u2081 u208b u2086 H or alkyl； n is 0, 1,2 or 3； r u00b3 u00b2 is alkyl c u2081 u208b u2086, coor u00b9 u00b3, conr u00b9 u2074r u00b9 u2075, S (OR) u2098r u00b9 u2076, Oh, CN, c u2083 u208b u2088 Heterocyclic cycloalkyl, bicicloalquilo c u2085 u208b u2088, 4, 5 or 6 members.PHENYL or heteroaryl Ring of 5 or 6 members； where c u2083 u208b u2088 cycloalkyl groups, bicicloalquilo c u2085 u208b u2088 heterocycle, 4, 5 or 6 members, phenylHeteroaryl Ring of 5 or 6 members may be optionally substituted with 1 to 3 groups selected from the list c u2081 u208b u2084 alcanoilo c u2081 u208b u2084 alkyl, Hydroxy alkyl, Hydroxy, c u2081 u208b u2084, c u2081 u208b u2086 alquiloxi,C u2081 u208b u2083 alkyl c u2081 u208b u2084 alquiloxi, Oxo, F and Cl； M is 0, 1 or 2； r u00b9 u00b3 is H or alkyl c u2081 u208b u2086； r u00b9 u2074, r u00b9 u2075 are, independently of one another, c u2083 u208b u2086 c u2081 u208b u2086 h, alkyl, cycloalkyl,C u2081 u208b u2086 substituted alkyl with 1 to 3 groups selected from the list or u00b9 u2077, coor u00b9 u2079 heterocycle and a 4, 5 or 6 members； or r u00b9 u2074 and r u00b9 u2075 constitute, together with the N Atom to which they are UnitedA heterocycle of 4, 5 or 6 members
