#$%^&*AU2014200511B220160721.pdf#####ABSTRACT The present invention relates to a method of treating congestive heart failure (CHF) in a subject comprising administering a peptide derived from atrial natriuretic peptide (ANP) prohormone (eg vessel dilator VSDL) or a mimetic thereof. In a particular application, the invention provides a method of 5 treating the particular indication known as acute decompensated congestive heart failure (ADCHF). Devices for intravenous or subcutaneous infusion for use in the method of the invention are also disclosed. 0