Disclosed herein are compositions comprising a targeted corrole nanoparticle and an acceptable excipient. Also disclosed are compositions comprising a targeted corrole nanoparticle and an acceptable carrier. Further, disclosed herein are methods of imaging a condition in a subject, comprising providing a composition comprising a targeted corrole nanoparticle administering an effective amount of the targeted corrole nanoparticle to the subject and imaging the condition in the subject. In addition, disclosed herein are methods of treating cancer in a subject, comprising providing a composition comprising a targeted corrole nano-particle and administering a therapeutically effective dosage of the targeted corrole nanoparticle to the subject.
