599031 Disclosed is a dosage form for administration of two active pharmaceutical ingredients to a Subject, comprising a first pharmaceutical composition comprising fluoxetine or a pharmaceutically acceptable salt thereof optionally one or more pharmaceutically acceptable excipients in a first physical form selected from the group consisting of powder or granule, pellet, bead or mini-tablet form, and a second pharmaceutical composition comprising olanzapine or a pharmaceutically acceptable salt thereof, and optionally one or more pharmaceutically acceptable excipients in a second physical form selected from the group consisting of granule, pellet, bead, mini-tablet or tablet form, and wherein said first and second physical forms are selected to be different to minimise interactions between said first and second pharmaceutical compositions and to allow separation of said first and second pharmaceutical compositions for analysis on the basis of size difference. Also disclosed is a method of making the dosage form.
