ELIS, WINFRIED,ETTENBERG, SETH,GARNER, ANDREW PAUL,KUNZ, CHRISTIAN CARSTEN SILVESTER,SEITZ, TOBIAS
申请号：
CA2857601
公开号：
CA2857601A1
申请日:
2012.12.04
申请国别(地区):
CA
年份:
2013
代理人:
摘要：
The present invention relates to antibodies or fragments thereof that target an epitope of a HER3 receptor residing in domain 2 of the HER3 receptor to block both ligand-dependent and ligand-independent signal transduction and tumor growth； and compositions and methods of use thereof.
