The use of taurine and/or hypotaurine and their salts in oral compositions for the prevention and treatment of aging of the pilosebaceous unit and/or alopecia. ACTIVITY : Endocrine-Gen. MECHANISM OF ACTION : Hair follicle alteration regulator； proline incorporation is reduced whilst leucine incorporation is unaffected. Two groups of 36 women aged 18 - 40 years having fine, limp and seborrheic hair were treated either with a composition as described or a placebo based on maltodextrin. The active formulation contained, per unit dose, taurine (159 mg), green tea extract (30 % catechins； 375 mg), grapeseed extract (40 % procyanidin oligomers, 20% catechins； 150 mg), zinc (as zinc sulfate； 15 mg). The number of hairs removed by three sweeps of the comb were counted after 0, 3, and 6 months, and the results are shown in the figure. After six months the number of hairs removed from the treated subjects averaged 40.5, whilst the number from untreated subjects was 56.7.La présente invention concerne l'utilisation de polyphénol(s) choisi(s) parmi les flavonols, anthocyanines, flavanols, proanthocyanidines et flavanones, et stilbènes pour la préparation d'une composition orale utile dans le traitement ou la prévention des désordres de l'unité pilo-sébacée.
