N-(Amino-heteroaryl)-1H-indole-2-carboxamide compounds (I) in the form of bases, acid addition salts, hydrates or solvates are new. N-(Amino-heteroaryl)-1H-indole-2-carboxamide compounds of formula (I) optionally in the form of bases, acid addition salts, hydrates or solvates, are new. X 1 : H, halo, 1-6C alkyl, 3-7C cycloalkyl, 3-7C cycloalkyl-1-3C alkylene, 1-6C fluoroalkyl, CN, C(O)NR 1R 2, NO 2, 1-6C thioalkyl, -S(O)-1-6C alkyl, -S-(O) 2-1-6C alkyl, -SO 2NR 1R 2, aryl-1-6C alkylene or T； T : (hetero)aryl (optionally substituted by halo, 1-6C alkyl, 3-7C cycloalkyl, 3-7C cycloalkyl-1-3C alkylene, 1-6C fluoroalkyl, 1-6C alkoxyl, 1-6C fluoroalkoxyl, NO 2 or CN)； X 2 : H, halo, 1-6C alkyl, 3-7C cycloalkyl, 3-7C cycloalkyl-1-3C alkylene, 1-6C fluoroalkyl, 1-6C alkoxyl, 3-7C cycloalkyl-1-3C alkylene-O-, 1-6C fluoroalkoxyl, CN, C(O)NR 1R 2, 1-6C-thioalkyl, -S(O)-1-6C alkyl-, -SO 2-alkyl-, SO 2-NR 1R 2, aryl-1-6C alkylene or T； X 3, X 4 : H, halo, 1-6C alkyl, 3-7C cycloalkyl, 3-7C cycloalkyl-1-3C alkylene, 1-6C fluoroalkyl, 1-6C alkoxyl, 3-7C cycloalkyl-1-3C alkylene-O-, 1-6C fluoroalkoxyl, CN, C(O)NR 1R 2, NO 2, NR 1R 2, 1-6C thioalkyl, -S(O)-1-6C alkyl, -S(O) 2-1-6C alkyl, -SO 2NR 1R 2, NR 3COR 4, NR 3SO 2R 5, aryl-1-6C alkylene or T； Z 1-Z 4 : N or C(R 6) (nitrogen atom present in the cycle i.e. defined as nitrogen position 1, is substituted by R 7 and the carbon atom in 2 or 4 position in relation to the reference nitrogen is substituted by thio or oxo group)； n : 0-3； Y 1 : (hetero)aryl (optionally substituted by halo, 1-6C alkyl, 3-7C cycloalkyl, 3-7C cycloalkyl-1-3C alkylene, 1-6C fluoroalkyl, OH, 1-6C alkoxyl, 3-7C cycloalkyl-1-6C alkylene-O-, 1-6C fluoroalkoxyl, CN, -C(O) NR 1R 2, NO 2, NR 1R 2, 1-6C thioalkyl, thiol, -S(O)-1-6C alkyl, -S(O) 2-1-6C alkyl, SO 2NR 1R 2, NR 3COR 4, -NR 3SO 2R 5, aryl-1-6C alkylene or aryl, where aryl-1-6C alkylene or aryl optionally substituted by halo, 1-6C alkyl, 3-7C cycloalkyl, 3-7C cycloalkyl-1-3C alkylene, 1-6C fluoroalkyl,
