The present invention provides a compound of formula (I) {Wherein, R 1 represents -NR 1a R 1b (wherein, R 1a and R 1b are the same or different, a hydrogen atom, an aralkyl, etc.) denote the like, R 2 is [Represents an integer of formula, k and m is 0~2, n represents an integer of 0 to 2, L represents a single bond or the like, R 5 represents a halogen, etc., R 6 represents an aryl, etc., X is (in the formula, R 8 represents a hydrogen atom or the like) -CR 8 represents the like, R 7 represents is a], and the like represent a hydrogen atom or the like, R 3 represents in -SO 2 R 13 [formula, R 13 is a lower alkoxy, in -NR 13d (C = O) R 13e (formula, R 13d is a hydrogen atom or the like, R 13e represents and the 'like represents a lower alkyl represents, etc.) or the like, R 4 to provide chemokine receptor activity regulating agent which contains a salt which is acceptable pyrazolopyrimidine derivative or a pharmaceutically represented by} represents a hydrogen atom or the like as an active ingredient.本発明は、式（I）｛式中、R1は-NR1aR1b（式中、R1a及びR1bは同一または異なって、水素原子、アラルキル等を表す）等を表し、R2は［式中、k及びmはそれぞれ0～2の整数を表し、nは0～2の整数を表し、Lは単結合等を表し、R5はハロゲン等を表し、R6はアリール等を表し、Xは-CR8（式中、R8は水素原子等を表す）等を表し、R7は水素原子等を表す］等を表し、R3は-SO2R13［式中、R13は低級アルコキシ、-NR13d(C=O)R13e（式中、R13dは水素原子等を表し、R13eは低級アルキル等を表す）等を表す］等を表し、R4は水素原子等を表す｝で表されるピラゾロピリミジン誘導体またはその薬学的に許容される塩を有効成分として含有するケモカイン受容体活性調節剤等を提供する。
