OLLERENSHAW, JEREMY,REICHART, EMILY,ROSS, RUSSELL F.
申请号:
CA2850931
公开号:
CA2850931A1
申请日:
2012.10.16
申请国别(地区):
CA
年份:
2013
代理人:
摘要:
An implantable delivery device and method for utilizing the device to delivery a bioactive agent to a subject in need thereof is described. The device includes a pattern of structures fabricated on a surface of the device to form a nanotopography. A random or non-random pattern of structures may be fabricated such as a complex pattern including structures of differing sizes and/or shapes. The device may be located adjacent tissue such as an endovascular implant or a perivascular implant, and may deliver the bioactive agent without triggering an immune or foreign body response to the bioactive agent.