Emma L. Carswell,Mark David Charles,Anne Cochi,Benjamin J. Dugan,Chukuemeka Tennyson Ekwuru,Fred Elustondo,Katherine M. Fowler,Frederic Georges Marie Leroux,Nathaniel J.T. Monck,Gregory R. Ott,Jonatha
申请号：
US16335379
公开号：
US20200123157A1
申请日:
2017.09.22
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present invention relates to compounds of formula (I), and salts and solvates thereof, that function as inhibitors of cell division cycle 7 (Cdc7) kinase enzyme activity:wherein X, R1, R2, and n are each as defined herein. The present invention also relates to processes for the preparation of these compounds, to pharmaceutical compositions comprising them, and to their use in the treatment of proliferative disorders, such as cancer, as well as other diseases or conditions in which Cdc7 kinase activity is implicated.
