YAGODICH MARY K.,CITRON MICHAEL P.,DISTEFANO DANIEL J.,KRAH DAVID L.,LIANG XIAOPING
申请号:
TN2011000182
公开号:
TN2011000182A1
申请日:
2011.04.19
申请国别(地区):
TN
年份:
2012
代理人:
摘要:
The present invention features live, attenuated respiratory syncytial viruses (RSV) useful as vaccines against RSV infection and/or the development of severe RSV-associated illnesses. The disclosed viruses are attenuated to the extent of being nonpathogenic when administered to a subject but substantially retain the antigenic and immunogenic properties of wild-type RSV.