THARRAULT FRANCOIS,타라울트, 프랑수와,POIRIER CECILE,프와르제, 세실,FONKNECHTEN GILLES,폰크내히텐, 질,PEAN JEAN MANUEL,핀, 장-마누엘
申请号：
KR1020120087177
公开号：
KR1020130018156A
申请日:
2012.08.09
申请国别(地区):
KR
年份:
2013
代理人:
摘要：
PURPOSE: A solid pharmaceutical composition containing agomelatine is provided to ensure bioavailability and to enable the control of releasing an active ingredient in the oral cavity. CONSTITUTION: A solid pharmaceutical composition for buccal administration contains agomelatine or a hydrate, a complex, a co-crystalline form, a crystalline form, a pharmaceutically acceptable acid or base addition salts thereof, and a diluent, a binder, a lubricant, a coating agent, a plasticizer, a flavoring agent, a counter-irritant, and a sweetener. The diluents are polyol or saccharides. The pharmaceutical composition is lozenge or pastille. The pharmaceutical composition contains 0.1-25 mg of agomelatine.본 발명은 전신 작용을 위해 의도된 아고멜라틴을 포함하는 고체 협측 약학적 조성물에 관한 것이다.
