Institut Jean Paoli & Irène Calmettes;INSERM (Institut National de la Santé et de la Recherche Médicale);Université d'Aix-Marseille;UNIVERSITE CLAUDE BERNARD - LYON 1;Centre Leon Berard
发明人:
申请号：
EP16195361.7
公开号：
EP3147297B1
申请日:
2012.03.29
申请国别(地区):
EP
年份:
2018
代理人:
摘要：
The present invention provides antibodies directed against ICOS or a derivative thereof which induce IL-10 and IFN³ production, induce CD4+ T cells proliferation, reduce Tconv proliferation, and increase the immunosuppressive function of Treg. The present invention also relates to uses of said antibodies for treating autoimmune diseases, transplantation rejection and graft versus host disease."
