PROBLEM TO BE SOLVED: To provide means effective in the prevention and/or treatment of fulminant acute pneumonia.SOLUTION: Provided are an agent or pharmaceutical composition used for preventing and/or treating fulminant acute pneumonia comprising CD11b antagonist, for example, an antibody specifically recognizing CD11b (anti-CD11b antibody) an intra-alveolar neutrophil aggregation inhibitor comprising CD11b antagonist, for example, an antibody specifically recognizing CD11b (anti-CD11b antibody) a pulmonary neutrophilic infiltration inhibitor comprising CD11b antagonist, for example, an antibody specifically recognizing CD11b (anti-CD11b antibody) and a method for preventing and/or treating fulminant acute pneumonia comprising administering CD11b antagonist, for example, an antibody specifically recognizing CD11b (anti-CD11b antibody).SELECTED DRAWING: NoneCOPYRIGHT: (C)2018,JPO&INPIT【課題】劇症型急性肺炎の予防及び/又は治療に有効な手段を提供すること。【解決手段】CD11bアンタゴニスト、例えばCD11bを特異的に認識する抗体(抗CD11b抗体)を含む、劇症型急性肺炎を予防及び/又は治療するために使用される薬剤又は医薬組成物、CD11bアンタゴニスト、例えばCD11bを特異的に認識する抗体(抗CD11b抗体)を含む、肺胞内の好中球凝集抑制剤、CD11bアンタゴニスト、例えばCD11bを特異的に認識する抗体(抗CD11b抗体)を含む、肺の好中球浸潤抑制剤、並びに、CD11bアンタゴニスト、例えばCD11bを特異的に認識する抗体(抗CD11b抗体)を投与することを含む、劇症型急性肺炎を予防及び/又は治療する方法。【選択図】なし
