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1,6-DIAZABICYCLO DERIVATIVES [3.2.1] OCTAN-7-ONE AND THEIR APPLICATION FOR TREATMENT OF BACTERIAL INFECTIONS
专利权人:
ВОКХАРДТ ЛИМИТЕД (IN)
发明人:
ПАТИЛ Виджаикумар Джагдишвар (IN),ТАДИПАРТХИ Равикумар (IN),ДОНД Бхарат (IN),КАЛЕ Амол (IN),ВЕЛУПИЛЛАИ Логанатхан (IN),ДЕКХАНЕ Дипак (IN),БИРАДЖДАР Сатиш Шримант (IN),ШАИКХ Мохаммад Усман (IN),МАУРЯ С
申请号:
RU2015110500
公开号:
RU2015110500A
申请日:
2013.04.19
申请国别(地区):
RU
年份:
2016
代理人:
摘要:
1. A compound of formula (I) or a stereoisomer thereof or a pharmaceutically acceptable salt thereof; wherein: R is: (a) SOM, (b) SONH, (c) POM, (d) CHCOOM, (e) CFCOOM, (f) CHFCOOM or (g) CF; M is hydrogen or a cation; R is: (a) hydrogen, (b) (CH) -R or (c) COORn is 0, 1 or 2; R is: (a) hydrogen, (b ) C-Calkyl optionally substituted with one or more substituents independently selected from halogen, OR, CN, COOR, CONRR, NRR, NRCOR, NRCONRR, heterocyclyl, heteroaryl, cycloalkyl or aryl, (c) CN, (d) NRR, ( e) CONRR, (f) NHCONRR, (g) aryl, optionally substituted with one or more substituents independently selected from C-C1-6 alkyl, OR, NRR, halogen, CN, CONRR, SO-alkyl, SO-aryl, OSO-alkyl, OSO-aryl or NHCONRR, (h) heterocyclyl, optionally substituted with one or more substituents, independently selected from C-C1-6 alkyl, OR, NRR, halogen, CN, CONRR, SO-alkyl, SO-aryl, OSO-alkyl, OSO-aryl or NHCONRR, (i) heteroaryl, optionally substituted with one or more substituents independently selected from C -Calkyl, OR, NRR, halogen, CN, CONRR, SO-alkyl, SO-aryl, OSO-alkyl, OSO-aryl or NHCONRR, (j) cycloalkyl optionally substituted with one or more substituents, optionally optionally selected from C-C1-6 alkyl, OR, NRR, halogen, CN, CONRR, SO-alkyl, SO-aryl, OSO-alkyl, OSO-aryl or NHCONRR, (k) cycloalkyl substituted with C-C1-6 alkyl, where C-C1-6 alkyl is optionally substituted by one or more substituents independently selected from OR, NRR, halogen, CN or CONRR, or (l) OR; R is: (a) hydrogen, (b) C-Calkyl optionally substituted by one or more substituents independently selected from halogen, OR, CN, COOR, CONRR, NRR, NRCOR, heterocyclyl, heteroaryl, cycloalkyl or aryl, (c) aryl, optionally substituted with one or more substituents, independently selected from C-C1-6 alkyl, OR, NRR, halogen, CN, CONRR, SO-alkyl, SO-aryl, OSO-alkyl, OSO-aryl or NHCONRR, (d) heterocyclyl, optionally substituted with one or more substituents independently selected from C-C1-6 alkyl, OR, NRR,1. Сое
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