CRYSTALS INCLUDING A MALIC ACID SALT OF N-[2-(DIETHYLAMINO) ETHYL]-5-[(5-FLUORO-2-OXO-3H-INDOLE-3-YLIDENE)METHYL]-2,4- DIMETHYL-1H-PYRROLE-3-CARBOXAMIDE, PROCESSES FOR ITS PREPARATION AND COMPOSITIONS THEREOF
HAWLEY, MICHAEL,FLECK, THOMAS J.,PRESCOTT, STEPHEN P.,MALONEY, MARK T.,HAWLEY, Michael,FLECK, Thomas J.,PRESCOTT, Stephen P.,MALONEY, Mark T.
申请号：
YUP10304
公开号：
RS53251B
申请日:
2002.08.13
申请国别(地区):
YU
年份:
2014
代理人:
摘要：
The present invention provides crystals, and compositions thereof, wherein the crystals include a malic acid salt of N-[2- (diethylamino)ethyl]-5-[(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide. Methods of preparing such crystals are also disclosed.Kristal koji sadrži so N-[2-(dietilamino)etil]-5-[(5-fluor-1,2-dihidro-2-okso-3H-indol-3-iliden)metil]-2,4-dimetil-1H-pirol-3-karboksamid L-jabučne kiseline, naznačen time, što ima karakteristične difrakcione pikove na 13.2° i 24.2° 2θ na rendgenskom dijagramu praha.Prijava sadrži još 10 patentnih zahteva.
