Disclosed is a composition comprising a benzo(c)chromen-6-one compound as depicted in the drawing as SG00529 or SG00574. 3-(4-methoxy-Benzyloxy)-8-(1-hydroxyethyl)-2-methoxy-6H-benzo[c]chromen-6-one is possibly the name of SG00529 Also disclosed is the use of the compounds for the manufacture of a medicament for preventing and/or treating a skin disease.