Hai-Feng Ji,Garth David Ehrlich,Donald Carl Hall, Jr.,Jaroslaw E. Krol,John P. Cahill
申请号:
US16610376
公开号:
US20200069647A1
申请日:
2018.05.14
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Pharmaceutical compositions comprising a RelA enzyme inhibitor and a bactericidal antibiotic, wherein said RelA enzyme inhibitor binds to the RelA enzyme in bacteria to reduce biofilm formation and to degrade biofilms that have been formed. The pharmaceutical compositions can be used to treat bacterial biofilm diseases.