SYSTEMES, PROCEDES ET COMPOSITION D'UTILISATION DE MUTANTS DE RNASE III POUR PRODUIRE UN ARNS POUR LUTTER CONTRE UNE INFECTION PAR UN AGENT PATHOGENE HOTE
YIN, GUOHUA,LEBRUN, ERICK SCOTT,TRAVERS, TIMOTHY S.
申请号：
CA3095489
公开号：
CA3095489A1
申请日:
2019.04.01
申请国别(地区):
CA
年份:
2019
代理人:
摘要：
The current invention includes systems, methods and compositions for the generation of sRNA molecules using select RNase III mutants. In one preferred embodiment, invention includes systems, methods and compositions for the generation of sRNA molecules using RNase III mutants to control a host pathogen through the production and diffusion of sRNA molecules that may initiate an RNAi pathway response directed to a host pathogen. Additional embodiments of the current invention include systems, methods and compositions for the DICER-independent generation of sRNA molecules using select RNase III mutants.
