BEBBINGTON, CHRISTOPHER ROBERT,TOMASEVIC, NENAD,FALAHATI, RUSTOM
申请号：
CA2939931
公开号：
CA2939931A1
申请日:
2015.02.27
申请国别(地区):
CA
年份:
2015
代理人:
摘要：
The invention provides methods and compositions for the prevention and treatment of Siglec-8 associated diseases such as chronic rhino sinusitis with concomitant asthma and aspirin- exacerbated respiratory disease. In particular, the invention provides methods for the prevention and treatment of Siglec-8 associated diseases through administration of antibodies or agonists that bind to human Siglec-8 or compositions comprising said antibodies or agonists. The invention also provides articles of manufacture or kits comprising antibodies or agonists that bind to human Siglec-8 for the prevention and treatment of Siglec-8 associated diseases such as chronic rhinosinusitis with concomitant asthma and aspirin-exacerbated respiratory disease.
