MOLECULE DE LIAISON A UN ANTIGENE A CONJUGAISON REGULEE ENTRE UNE CHAINE LOURDE ET UNE CHAINE LEGERE

• 收藏
• 分享

专利权人:

CHUGAI SEIYAKU KABUSHIKI KAISHA

发明人:

KURAMOCHI, TAICHI,KAWAZOE, MEIRI,HIRONIWA, NAOKA,IGAWA, TOMOYUKI

申请号：

CA2853230

公开号：

CA2853230A1

申请日:

2012.10.31

申请国别(地区):

CA

年份:

2013

代理人:

摘要：

It is found that the conjugation between CH1 and CL can be inhibited and a hetero molecule can be formed more efficiently than a case in which a mutation of introducing a knob and a hole singly into CH3 is employed when an amino acid residue present on the interface between CH1 and CL is substituted by an amino acid residue having an electrical charge.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/