Provided is a prophylactic/therapeutic agent for dry eye, which comprises a novel component capable of preventing the deterioration of a tear fluid secretion ability and also capable of inhibiting the generation of active oxygen in tear gland tissues. The prophylactic/therapeutic agent for dry eye according to the present invention contains a maqui berry extract as an active ingredient. The prophylactic/therapeutic agent for dry eye according to the present invention may contain, as an active ingredient, a delphinidin glycoside that is extracted from maqui berry. The prophylactic/therapeutic agent for dry eye according to the present invention may contain at least one component selected from delphinidin-3-sambubioside-5-glucoside, delphinidin-3,5-diglucoside, delphinidin-3-sambubioside and delphinidin-3-glucoside, desirably delphinidin-3,5-diglucoside, as an active ingredient.