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ABUSE-RESISTANT CONTROLLED-RELEASE OPIOID DOSAGE FORM
专利权人:
Frank S. Caruso
发明人:
Frank S. Caruso,Huai-Hung Kao
申请号:
US13494431
公开号:
US20120252832A1
申请日:
2012.06.12
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Abuse-resistant, controlled release opioid tablets are a combination containing an opioid antagonist such as naloxone at a level above that needed to suppress the euphoric effect of the opioid, if the combination were crushed to break the controlled release properties causing the opioid and opioid antagonist to be released as an immediate release product as a single dose. The controlled release nature of the tablet prevents the accumulation of orally effective amounts of opioid antagonist when taken normally. The opioid antagonist is contained in a controlled-release matrix and released, over time, with the opioid.
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中国工程科技知识中心
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