An intraosseous nerve denervation device, comprises a first probe having an active electrode and a first lead, and a second probe having a return electrode and a second lead. The device includes means for creating first and second bores within a bone for accommodating the first and second probes, and a power supply capable of generating a voltage difference between the active and return electrodes, the supply having third and fourth leads. The first and third leads are in electrical connection, and the second and fourth leads are in electrical connection.