James Bradner,Justin Roberts,Behnam Nabet,Georg Winter,Andrew J. Phillips,Timothy Heffernan,Dennis Buckley
申请号:
US15889963
公开号:
US20180169109A1
申请日:
2018.02.06
申请国别(地区):
US
年份:
2018
代理人:
摘要:
This invention is in the area of compositions and methods for regulating chimeric antigen receptor immune effector cell, for example T-cell (CAR-T), therapy to modulate associated adverse inflammatory responses, for example, cytokine release syndrome and tumor lysis syndrome, using targeted protein degradation.