Song Young Kim;Jae Kap Jeong;Yeon Jung Song;Sung Wuk Kim;Sung Soo Jun;Seung Kook Park;Ha Na Kim;Eun Sun Kim
发明人:
Sung Wuk Kim,Sung Soo Jun,Seung Kook Park,Song Young Kim,Eun Sun Kim,Jae Kap Jeong,Ha Na Kim,Yeon Jung Song
申请号：
US13502675
公开号：
US20120251486A1
申请日:
2010.10.19
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention relates to a modified human tumor necrosis factor receptor-1 polypeptide to be coupled to a tumor necrosis factor in vivo or ex vivo, or to a fragment thereof. The modified human tumor necrosis factor receptor-1 polypeptide or the fragment thereof according to the present invention exhibit improved resistance against in vivo protease activity, and thus exhibit improved bioavailability and an improved absorption rate.
