BARTHOLOMÄUS, JOHANNES,KUGELMANN, HEINRICH,ARKENAU-MARIC, ELISABETH
申请号：
PL05769988
公开号：
PL1765303T3
申请日:
2005.06.29
申请国别(地区):
PL
年份:
2013
代理人:
摘要：
The invention relates to an oral dosage form, which is safeguarded against abuse and which has a controlled opioid release for a once daily administering. The invention is characterized in that the oral dosage form comprises at least one opioid with an abuse potential (A), at least one synthetic and/or natural polymer (C), optionally comprises retarding matrix materials, physiologically compatible adjuvants (B), optionally comprises a wax (D), and optionally comprises at least one retarding coating. Constituents (C) or (D) each have a breaking resistance of at least 500 N, preferably at least 750 N.
