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Method of identifying whether or not an individual has Parkinsons Disease rather than another neurodegenerative disease
专利权人:
Omar El-Agnaf
发明人:
Omar El-Agnaf,Lucilla Parnetti,Paolo Calabresi
申请号:
US13807963
公开号:
US08778334B2
申请日:
2011.07.06
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present invention relates to method of identifying whether or not an individual has Parkinsons disease (PD). In particular, the invention relates to a method for identifying whether or not an individual has PD as opposed to another neurodegenerative disease. The method of the invention comprises measuring the concentration of α-synuclein (α-syn) and the concentration of unphosphorylated tau (tau) and/or phosphorylated tau (p-tau) in a cerebrospinal fluid sample taken from an individual. The method also comprises calculating the ratio of the concentration of tau and/or p-tau to the concentration of α-syn, and thereby determining whether or not the individual has PD.
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