Mary K. Yagodich;Michael P. Citron;Daniel L. Krah;Daniel J. Distefano;Xiaoping Liang
发明人:
Mary K. Yagodich,Michael P. Citron,Daniel J. Distefano,Daniel L. Krah,Xiaoping Liang
申请号:
US13127647
公开号:
US09011876B2
申请日:
2009.11.03
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention features live, attenuated respiratory syncytial viruses (RSV) useful as vaccines against RSV infection and/or the development of severe RSV-associated illnesses. The disclosed viruses are attenuated to the extent of being nonpathogenic when administered to a subject but substantially retain the antigenic and immunogenic properties of wild-type RSV.