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2-amino-6-(difluoromethyl)-5,5-difluoro-6-phenyl-3,4,5,6-tetrahydropyridines as BACE1 inhibitors
专利权人:
H. Lundbeck A/S
发明人:
Karsten Juhl,Lena Tagmose,Mauro Marigo
申请号:
US15524546
公开号:
US10045974B2
申请日:
2015.11.09
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention is directed to compounds of formula (I) which are inhibitors of the BACE1 enzyme. Separate aspects of the invention are directed to pharmaceutical compositions comprising said compounds and uses of the compounds to treat disorders for which the reduction of Aβ deposits is beneficial such as Alzheimer's disease.
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