Colin M. Tice;Zhenrong Xu;Patrick T. F;Jing Yuan;Robert D. Simpson;Suresh B. Singh;John J. Baldwin;David A. Claremon;Alexey V. Ishchenko;Gerard McGeehan;Wei Zhao;Lawrence W. Dillard;Salvacion Cacatian
发明人:
John J. Baldwin,David A. Claremon,Colin M. Tice,Salvacion Cacatian,Lawrence W. Dillard,Alexey V. Ishchenko,Jing Yuan,Zhenrong Xu,Gerard McGeehan,Wei Zhao,Robert D. Simpson,Suresh B. Singh,Patrick T. F
申请号：
US12802142
公开号：
US08455521B2
申请日:
2010.05.28
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Diaminoalkanes of below Formula I have now been found which are orally active and bind to aspartic proteases to inhibit their activity:They are useful in the treatment or amelioration of diseases associated with elevated levels of aspartic protease activity. The invention also relates to a method for the use of the compounds of Formula I in ameliorating or treating aspartic protease related disorders in a subject in need thereof comprising administering to said subject an effective amount of a compound of Formula I.
