INACTIVATED POLIOVACCINE

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专利权人:

发明人:

申请号：

EP11807966.4

公开号：

EP2658571B1

申请日:

2011.12.29

申请国别(地区):

EP

年份:

2016

代理人:

摘要：

The invention provides an attenuated polio virus having a 5′ non-coding region consisting of the 5′ non-coding region of Sabin 3, modified so that it does not have a base pair mismatch in stem (a) or (b) of domain V, wherein seven or eight of the base pairs in stems (a) and (b) are U-A or A-U base pairs and a capsid protein from the Sabin 1, Mahoney, MEF or Saukett strain.

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