The University Court of the University of Glasgow;Georgia Tech Research Corporation
发明人:
Manuel SALMERON-SANCHEZ,Matthew J. DALBY,Andres J. GARCIA
申请号:
US15576718
公开号:
US20180133364A1
申请日:
2016.05.26
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The invention provides materials presenting a biologically active matrix comprising a physiological fibrillar fibronectin network, such as implantable constructs, and their use for modulating cell behaviour and fate, including cell growth, proliferation and/or differentiation, such as for promoting tissue regeneration, for example, bone regeneration or vascularization. Also provided are constructs presenting a biologically active matrix comprising a physiological fibrillar fibronectin network for sustaining growth of stem cells or maintaining stem cells (maintaining stemness).